Author’s response to reviews Title: (R)-α-Lipoic acid inhibits fructose-induced myoglobin fructation and the formation of advanced glycation end products (AGEs) in vitro Authors:
نویسندگان
چکیده
Title: (R)-α-Lipoic acid inhibits fructose-induced myoglobin fructation and the formation of advanced glycation end products (AGEs) in vitro Authors: Hardik Ghelani ([email protected]) Valentina Razmovski-Naumovski ([email protected]) Rajeswara Pragada ([email protected]) Srinivas Nammi ([email protected]) Version: 1 Date: 18 Nov 2017 Author’s response to reviews:
منابع مشابه
(R)-α-Lipoic acid inhibits fructose-induced myoglobin fructation and the formation of advanced glycation end products (AGEs) in vitro
BACKGROUND Fructose-mediated protein glycation (fructation) has been linked to an increase in diabetic and cardiovascular complications due to over consumption of high-fructose containing diets in recent times. The objective of the present study is to evaluate the protective effect of (R)-α-lipoic acid (ALA) against fructose-induced myoglobin fructation and the formation of advanced glycation e...
متن کاملAttenuation of Glucose-Induced Myoglobin Glycation and the Formation of Advanced Glycation End Products (AGEs) by (R)-α-Lipoic Acid In Vitro
High-carbohydrate containing diets have become a precursor to glucose-mediated protein glycation which has been linked to an increase in diabetic and cardiovascular complications. The aim of the present study was to evaluate the protective effect of (R)-α-lipoic acid (ALA) against glucose-induced myoglobin glycation and the formation of advanced glycation end products (AGEs) in vitro. METHODS...
متن کاملSalvia reuterana Extract Prevents Formation of Advanced Glycation End Products: An In Vitro Study
In this study, we examined the antioxidant activities of methanolic extract of three endemic species of Salvia from Iran (S. lachno...
متن کاملFructation induced cross-linking of beta-lactoglobulin and lysozyme.
Protein glycation (non-enzymatic glycosylation) and the development of advanced glycation end-products (AGEs) is strongly associated with the pathogenesis of diabetic secondary complications [I ] . Hydroxyl radicals generated from superoxide via the Fenton reaction have been implicated for in virro AGE formation [2]. The term glycoxidation has been coined to emphasise the involvement of metal c...
متن کاملMesona Chinensis Benth extract prevents AGE formation and protein oxidation against fructose-induced protein glycation in vitro
BACKGROUND Mesona chinensis Benth (Chinese Mesona), an economically significant agricultural plant, is the most widely consumed as an herbal beverage in Southeast Asia and China. The objective of this study was to evaluate the inhibitory activity of Mesona chinensis (MC) extract on the formation of advanced glycation end products (AGEs) and protein oxidation in an in vitro model of fructose-med...
متن کامل